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Consequently, Anavar is in high demand by gym-goers who want to take their body to the next level without having to worry about jeopardizing their health. Despite being an oral steroid , Anavar does not pose much stress to the liver. This may be due to the kidneys also helping to process the compound, in effect taking the work-load off the liver. In research, 20mg per day does not seem to affect the liver (7), whereas 40mg per day increases liver enzymes by 30-50%. Male bodybuilders will typically take a maximum dose of 20mg. Anavar will cause some testosterone suppression. Such reductions are likely to be mild to moderate, taking several weeks to return to normal levels. As test levels will not be shut down fully, a post cycle therapy is deemed unnecessary by some users. Anavar does have a negative effect on cholesterol levels , worse than testosterone, yet is considerably safer than other injectables and oral steroids. 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